Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719304371-gr1.jpg)
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS](https://www.pnas.org/cms/10.1073/pnas.2100225118/asset/db848d79-1de7-4bc4-bde9-b07b4a767884/assets/images/large/pnas.2100225118fig05.jpg)
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS
![Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.9b01039/asset/images/large/jm9b01039_0001.jpeg)
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry
![miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram](https://www.researchgate.net/publication/316843590/figure/fig5/AS:1091459621101624@1637235660787/miniCTT-mediates-activation-of-DCs-A-BFP-and-CD86-expression-in-DCs-4-d-after.jpeg)
miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram
![STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling](https://www.science.org/cms/10.1126/scisignal.aah5054/asset/9740249a-b5ff-4887-8378-d729d3b87f42/assets/graphic/aah5054-f1.jpeg)
STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS](https://www.pnas.org/cms/10.1073/pnas.2100225118/asset/a7033003-7eb9-468c-81fa-597f27b1856d/assets/images/large/pnas.2100225118fig01.jpg)
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS
![Frontiers | Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy Frontiers | Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy](https://www.frontiersin.org/files/Articles/954129/fimmu-13-954129-HTML-r1/image_m/fimmu-13-954129-g002.jpg)
Frontiers | Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy
![TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124720303703-fx1.jpg)
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect
![TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS](https://www.pnas.org/cms/10.1073/pnas.2100225118/asset/9994c6cc-8389-43ff-9a3e-d1ce1024c2c0/assets/images/large/pnas.2100225118fig03.jpg)
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719304371-gr3.jpg)