PDB-101: Molecule of the Month: Cisplatin and DNA
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis - ScienceDirect
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication | PLOS Genetics
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
DNA polymerases and cancer | Nature Reviews Cancer
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Translesion DNA synthesis in the context of cancer research | Cancer Cell International | Full Text
In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C - ScienceDirect
Regulation of the error-prone DNA polymerase polκ by oncogenic signaling and its contribution to drug resistance | bioRxiv
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Unravelling roles of error-prone DNA polymerases in shaping cancer genomes | Oncogene
-Western-Blot-H00051426-M01-img0015.jpg "DNA Polymerase Kappa Research Products: Novus Biologicals")
DNA Polymerase Kappa Research Products: Novus Biologicals
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
RCSB PDB - 6CST: Structure of human DNA polymerase kappa with DNA
DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation | Oncogene
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells | Biochemistry
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
