Neurodegenerative diseases distinguished through protein-structure analysis
Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson's disease | Communications Biology
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration | Nature
PDF) Structural and functional characterization of two a-synuclein strains
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel | Nature Communications
Structural and functional characterization of two alpha-synuclein strains | Nature Communications
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity | PNAS
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb | Acta Neuropathologica Communications | Full Text
Evidence of distinct α-synuclein strains underlying disease heterogeneity | SpringerLink
α-Synuclein strains target distinct brain regions and cell types | Nature Neuroscience
Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy | Nature
Frontiers | New Perspectives on Roles of Alpha-Synuclein in Parkinson's Disease | Frontiers in Aging Neuroscience
Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons: Cell
Stabilization of α-synuclein oligomers using formaldehyde
Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts | Nature Communications
Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network - ScienceDirect
Molecules | Free Full-Text | Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro | HTML
The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding | Scientific Reports
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb | Acta Neuropathologica Communications | Full Text
Hsp110 mitigates α-synuclein pathology in vivo | PNAS
Frontiers | In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons | Cell and Developmental Biology
Distinct α-Synuclein strains and implications for heterogeneity among α-Synucleinopathies - ScienceDirect
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies | Nature
